This study observed the effectiveness of UC-MSC Stem Cells in alleviating Prader-Willi syndromes. One good reason was that UC-MSC with a wide variety of stem cells is well-sourced and easy to collect and preserve. It also has the capability of multi-directional differentiation. It can differentiate into bone, adipose, cartilage, and other tissues and meet this endeavor's intended purpose. Besides it, UC-MSC is also the product of Celltech Stem Cell Laboratory & Banking (CSC) where this study is initiated. Experiments were applied on patients of different sexes to see the results of the treatments where both meet satisfactory expectations.