Profile Comorbid Factors, Age, and Gender Relationship with Severity of Pulmonary Infection Caused by COVID-19 Pulmonary Infection for the Period of June to August 2021 at Sidoardjo Regional General Hospital
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COVID-19 transmission has three main mechanisms, namely host conditions, viral virulence, and environmental factors. Transmission is higher in individuals with weakened immune systems and those in vulnerable groups, especially those with comorbidities. This study aims to determine the profile and role of comorbid factors, age, and gender relationship with the clinical severity of covid-19 pulmonary infection for the periode of june to august 2021 at sidoardjo regional general hospital Comorbidities such as diabetes mellitus and cardiovascular disease have been shown to be significant risk factors for death in COVID-19 patients. Previous results have shown that men, advanced age, as well as the presence of comorbidities such as diabetes and hypertension, increase the risk of death from COVID-19. This study uses secondary data from the medical records of COVID-19 patients to evaluate patient profiles based on age, gender, and comorbidities. The results of this study are expected to provide a deeper understanding of the influence of these factors on the severity and risk of death from COVID-19, as well as support future disease prevention and control efforts.
Chen, T., Dai, Z., Mo, P., Li, X., Ma, Z., Song, S., Chen, X., Luo, M., Liang, K., & Gao, S. (2020). Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China: a single-centered, retrospective study. The Journals of Gerontology: Series A, 75(9), 1788–1795. https://doi.org/10.1093/gerona/glaa089
Elrashdy, F., Redwan, E. M., & Uversky, V. N. (2020). Why COVID-19 transmission is more efficient and aggressive than viral transmission in previous coronavirus epidemics? Biomolecules, 10(9), 1312.
Fathi, M., Vakili, K., Sayehmiri, F., Mohamadkhani, A., Hajiesmaeili, M., Rezaei-Tavirani, M., & Eilami, O. (2021). The prognostic value of comorbidity for the severity of COVID-19: A systematic review and meta-analysis study. PloS one, 16(2), e0246190.
Garibaldi, B. T., Fiksel, J., Muschelli, J., Robinson, M. L., Rouhizadeh, M., Perin, J., Schumock, G., Nagy, P., Gray, J. H., & Malapati, H. (2021). Patient trajectories among persons hospitalized for COVID-19: a cohort study. Annals of internal medicine, 174(1), 33–41.
Hendren, N. S., De Lemos, J. A., Ayers, C., Das, S. R., Rao, A., Carter, S., Rosenblatt, A., Walchok, J., Omar, W., & Khera, R. (2021). Association of body mass index and age with morbidity and mortality in patients hospitalized with COVID-19: results from the American Heart Association COVID-19 Cardiovascular Disease Registry. Circulation, 143(2), 135–144.
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., & Gu, X. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet, 395(10223), 497–506.
Joly, F., Baxter, J., Staun, M., Kelly, D. G., Hwa, Y. L., Corcos, O., De Francesco, A., Agostini, F., Klek, S., & Santarpia, L. (2018). Five-year survival and causes of death in patients on home parenteral nutrition for severe chronic and benign intestinal failure. Clinical Nutrition, 37(4), 1415–1422.
Karlsen, L. (2025). Hospital at home for adults A qualitative study of implementation and care delivery in a Norwegian healthcare context.
Ketelaers, S. H. J., Orsini, R. G., Burger, J. W. A., Nieuwenhuijzen, G. A. P., & Rutten, H. J. T. (2019). Significant improvement in postoperative and 1-year mortality after colorectal cancer surgery in recent years. European Journal of Surgical Oncology, 45(11), 2052–2058.
Kirubananthan, L., Illuri, R., Rajendran, R., & Chandrasekaran, P. R. (2021). Mechanism and transmission routes of COVID-19. In Environmental and Health Management of Novel Coronavirus Disease (COVID-19) (hal. 65–88). Elsevier.
Louten, J. (2016). Virus transmission and epidemiology. Essential human virology, 71.
Maulidah, A. (2023). Literature Review: Knowledge of Clean and Healthy Living Behaviors (PHBS) in Elementary School-Aged Children. Health Frontiers: Multidisciplinary Journal for Health Professionals, 1(1), 54–61.
Misbah, A. R. K., Murfat, Z., & Kanang, I. L. D. (2022). Analysis of Comorbidity Disease as A Risk Factor COVID-19 Death. Nusantara Science and Technology Proceedings, 72–83.
Purba, N., & Gusar, M. R. S. (2020). Clean and healthy lifestyle behavior (PHBS Program) for children with intellectual disability. Jurnal Pendidikan Usia Dini, 14(2), 275–287.
Suardi, M., & Aresti, A. (2022). Clinical Outcomes of Antiviral Therapy on Comorbid and non-Comorbid T2-DM COVID-19 Patients at Rasidin Hospital Luaran Klinik Terapi Antivirus pada Pasien Komorbid dan non-Komorbid T2-DM COVID-19 di RSUD Rasidin.
Tenbensel, T. (2015). 22. Complexity and health policy. Handbook on complexity and public policy, 369.
VanderWaal, K. L., & Ezenwa, V. O. (2016). Heterogeneity in pathogen transmission. Functional Ecology, 30(10), 1606–1622.
Yasin, Z., Nawawi, A., Devy, S. R., & Rahayu, S. (2025). The Effect of Family Clean and Healthy Living Behavior Education (PHBS) on the Prevention of Diarrhea in Toddlers. vol, 13, 94–102.
Zhu, Z., Lian, X., Su, X., Wu, W., Marraro, G. A., & Zeng, Y. (2020). From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses. Respiratory research, 21, 1–14.
