Preventive Effect Nanoparticles Moringa Oleifera of Supplementation During Pregnancy Care on Preeclampsia and Anxiety: Study Serotonin Levels
Main Article Content
Preeclampsia, a condition occurring in the third trimester of pregnancy, causes hypertension in mothers and contributes to higher rates of morbidity and mortality among maternal, fetal, and neonatal populations. Non-pharmacological management of hypertension includes using Moringa leaves processed with nanoparticle technology. As a preventive measure, the WHO recommends calcium supplementation for pregnant women. Research indicates that Moringa leaves are rich in flavonoids, calcium, and antioxidants beneficial for expectant mothers. This study aims to demonstrate the efficacy of Moringa Oleifera nanoparticles in reducing anxiety levels and blood pressure in pregnant women with hypertension through a randomized controlled trial. The experiment involved two groups: one receiving Moringa Oleifera nanoparticle extract and a control group. Forty pregnant women with hypertension, averaging 28.60 years old, participated in the study. Results showed significant differences in the treatment group before and after intervention (p<0.001). Moringa Oleifera nanoparticles reduced systolic (138.70±124.90, p=0.007), diastolic (88.50±78.40, p=0.045) blood pressure, increased serotonin levels (200.6±127.6), and decreased anxiety levels (HARS scale) (23.30±16.40, p=0.007). This study confirms that Moringa Oleifera nanoparticles effectively reduce serotonin levels, anxiety, and blood pressure in pregnant women with hypertension.
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