Meta-Analysis of the Effects of Barberry Consumption on Blood Pressure in Non-Communicable Disease Patients
Main Article Content
This study delves into the potential benefits of barberry consumption on blood pressure in individuals with hypertension and its effects on various non-communicable diseases. Barberry was chosen for investigation due to its historical use in traditional medicine and emerging evidence suggesting its positive impact on health. Barberry contains bioactive compounds like berberine, which have been associated with cardiovascular health benefits such as lowering blood pressure and cholesterol levels. Given the rising prevalence of hypertension and other non-communicable diseases globally, understanding the potential therapeutic effects of barberry could offer novel preventive and therapeutic strategies. Through the systematic review and meta-analysis of relevant literature, this study aims to provide a comprehensive assessment of the efficacy of barberry in managing blood pressure and its implications for public health interventions targeting non-communicable diseases.
Keywords:
Barberry, Blood Pressure, Communicable Disease
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Ma, C., Zheng, X., Yang, Y., & Bu, P. (2021). The effect of black tea supplementation on blood pressure: a systematic review and dose–response meta-analysis of randomized controlled trials. Food & Function, 12(1), 41–56. https://doi.org/10.1039/D0FO02122A
Safari, Z., Farrokhzad, A., Ghavami, A., Fadel, A., Hadi, A., Rafiee, S., Mokari-Yamchi, A., & Askari, G. (2020). The effect of barberry (Berberis vulgaris L.) on glycemic indices: A systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 51, 102414. https://doi.org/10.1016/j.ctim.2020.102414
Sethi, Y., Uniyal, N., Vora, V., Agarwal, P., Murli, H., Joshi, A., Patel, N., Chopra, H., Hasabo, E. A., & Kaka, N. (2023). Hypertension the ‘Missed Modifiable Risk Factor’ for Diabetic Neuropathy: a Systematic Review. Current Problems in Cardiology, 48(4), 101581. https://doi.org/10.1016/j.cpcardiol.2022.101581
Toniolo, J., Ngoungou, E. B., Preux, P.-M., & Beloni, P. (2024). Role and knowledge of nurses in the management of non-communicable diseases in Africa: A scoping review. PLOS ONE, 19(4), e0297165. https://doi.org/10.1371/journal.pone.0297165
Vatanabe, I. P., Manzine, P. R., & Cominetti, M. R. (2020). Historic concepts of dementia and Alzheimer’s disease: From ancient times to the present. Revue Neurologique, 176(3), 140–147. https://doi.org/10.1016/j.neurol.2019.03.004
Amini, M. R., Sheikhhossein, F., Naghshi, S., Djafari, F., Askari, M., Shahinfar, H., Safabakhsh, M., Jafari, A., & Shab-Bidar, S. (2020). Effects of berberine and barberry on anthropometric measures: A systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 49, 102337. https://doi.org/10.1016/j.ctim.2020.102337
Antar, S. A., Ashour, N. A., Sharaky, M., Khattab, M., Ashour, N. A., Zaid, R. T., Roh, E. J., Elkamhawy, A., & Al-Karmalawy, A. A. (2023). Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments. Biomedicine & Pharmacotherapy, 168, 115734. https://doi.org/10.1016/j.biopha.2023.115734
Association, A. D. (2014). Diagnosis and classification of diabetes mellitus. Diabetes Care, 37(Supplement_1), S81–S90.
Atefi, M., Ghavami, A., Hadi, A., & Askari, G. (2021). The effect of barberry (Berberis vulgaris L.) supplementation on blood pressure: A systematic review and meta-analysis of the randomized controlled trials. Complementary Therapies in Medicine, 56, 102608. https://doi.org/10.1016/j.ctim.2020.102608
Babashahi, S., Hansen, P., & Sullivan, T. (2021). Creating a priority list of non-communicable diseases to support health research funding decision-making. Health Policy, 125(2), 221–228. https://doi.org/10.1016/j.healthpol.2020.12.003
Belwal, T., Bisht, A., Devkota, H. P., Ullah, H., Khan, H., Pandey, A., Bhatt, I. D., & Echeverría, J. (2020). Phytopharmacology and Clinical Updates of Berberis Species Against Diabetes and Other Metabolic Diseases. Frontiers in Pharmacology, 11. https://doi.org/10.3389/fphar.2020.00041
Choudhury, A. A., & Rajeswari, V. D. (2021). Gestational diabetes mellitus-A metabolic and reproductive disorder. Biomedicine & Pharmacotherapy, 143, 112183.
Emamat, H., Zahedmehr, A., Asadian, S., & Nasrollahzadeh, J. (2022a). The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial. BMC Complementary Medicine and Therapies, 22(1), 59. https://doi.org/10.1186/s12906-022-03539-8
Emamat, H., Zahedmehr, A., Asadian, S., & Nasrollahzadeh, J. (2022b). The effect of purple-black barberry (Berberis integerrima) on blood pressure in subjects with cardiovascular risk factors: a randomized controlled trial. Journal of Ethnopharmacology, 289, 115097. https://doi.org/10.1016/j.jep.2022.115097
Emamat, H., Zahedmehr, A., Asadian, S., Tangestani, H., & Nasrollahzadeh, J. (2020). Effect of barberry (Berberis vulgaris) consumption on blood pressure, plasma lipids, and inflammation in patients with hypertension and other cardiovascular risk factors: study protocol for a randomized clinical trial. Trials, 21(1), 986. https://doi.org/10.1186/s13063-020-04918-7
Endalamaw, A., Khatri, R. B., Erku, D., Nigatu, F., Zewdie, A., Wolka, E., & Assefa, Y. (2023). Successes and challenges towards improving quality of primary health care services: a scoping review. BMC Health Services Research, 23(1), 893.
Hadi, A., Arab, A., Ghaedi, E., Rafie, N., Miraghajani, M., & Kafeshani, M. (2019). Barberry (Berberis vulgaris L.) is a safe approach for management of lipid parameters: A systematic review and meta?analysis of randomized controlled trials. Complementary Therapies in Medicine, 43, 117–124. https://doi.org/10.1016/j.ctim.2019.01.017
Haq, T., Ahmed, T., Latif, Z. A., Sayeed, M. A., & Ashrafuzzaman, S. M. (2019). Cardiac autonomic neuropathy in patients with type 2 diabetes mellitus having peripheral neuropathy: A cross-sectional study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(2), 1523–1528. https://doi.org/10.1016/j.dsx.2019.03.015
Kermani, T., Kazemi, T., Molki, S., Ilkhani, K., & Sharifzadeh, G. R. (2020). The Effect of Berberis vulgaris (Barberry Fruit) on a Component of Metabolic Syndrome: A Randomized Clinical Trial. Modern Care Journal, 17(2). https://doi.org/10.5812/modernc.93955
Lazavi, F., Mirmiran, P., Sohrab, G., Nikpayam, O., Angoorani, P., & Hedayati, M. (2018). The barberry juice effects on metabolic factors and oxidative stress in patients with type 2 diabetes: A randomized clinical trial. Complementary Therapies in Clinical Practice, 31, 170–174. https://doi.org/10.1016/j.ctcp.2018.01.009
Lee, K. J., & Lee, Y. J. (2016). Effects of vitamin D on blood pressure in patients with type 2 diabetes mellitus. Int. Journal of Clinical Pharmacology and Therapeutics, 54(04), 233–242. https://doi.org/10.5414/CP202493
Lipert, A., Szadkowska, I., Matusiak-Wieczorek, E., & Kochan, E. (2022). The Effect of Herbal Supplements on Blood Pressure: Systematic Review and Meta-Analysis. Antioxidants, 11(8), 1419. https://doi.org/10.3390/antiox11081419
Ma, C., Zheng, X., Yang, Y., & Bu, P. (2021). The effect of black tea supplementation on blood pressure: a systematic review and dose–response meta-analysis of randomized controlled trials. Food & Function, 12(1), 41–56. https://doi.org/10.1039/D0FO02122A
Safari, Z., Farrokhzad, A., Ghavami, A., Fadel, A., Hadi, A., Rafiee, S., Mokari-Yamchi, A., & Askari, G. (2020). The effect of barberry (Berberis vulgaris L.) on glycemic indices: A systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 51, 102414. https://doi.org/10.1016/j.ctim.2020.102414
Sethi, Y., Uniyal, N., Vora, V., Agarwal, P., Murli, H., Joshi, A., Patel, N., Chopra, H., Hasabo, E. A., & Kaka, N. (2023). Hypertension the ‘Missed Modifiable Risk Factor’ for Diabetic Neuropathy: a Systematic Review. Current Problems in Cardiology, 48(4), 101581. https://doi.org/10.1016/j.cpcardiol.2022.101581
Toniolo, J., Ngoungou, E. B., Preux, P.-M., & Beloni, P. (2024). Role and knowledge of nurses in the management of non-communicable diseases in Africa: A scoping review. PLOS ONE, 19(4), e0297165. https://doi.org/10.1371/journal.pone.0297165
Vatanabe, I. P., Manzine, P. R., & Cominetti, M. R. (2020). Historic concepts of dementia and Alzheimer’s disease: From ancient times to the present. Revue Neurologique, 176(3), 140–147. https://doi.org/10.1016/j.neurol.2019.03.004
