Chronic wounds are wounds whose healing phase does not match the physiological phase of wound healing. Chronic wounds, characterized by wounds that do not undergo a regular, regular, and timely repair process, remain a significant clinical challenge for healthcare professionals worldwide. As PRP treatments gain momentum in clinical settings, this meta-analysis seeks to offer an evidence-based perspective on their role in chronic wound management, paving the way for informed clinical practice and future research directions. This study aimed to systematically identify the effectiveness of platelet-rich plasma clothing in accelerating chronic wound healing. The studies predominantly employed Randomized Control Trials (RCTs) to evaluate treatments for various wound etiologies, including diabetic, venous, arterial, and mixed. Key outcomes gauged encompassed wound closure rate, size reduction, and other related parameters. While most studies showcased PRP's effectiveness, particularly in dressing form, there was a noticeable heterogeneity among the results. In a side exploration, PRP dressing was juxtaposed against PRP injection, revealing both methods' merits in wound management. In conclusion, while PRP treatments, be it in dressing or injectable form, offer potential benefits for chronic wound healing, the variability in study outcomes highlights the need for more standardized research methodologies.