The Use of Quantum Stem
Cell Therapy for Autoimmune Diseases Treatment
Deby Susanti Pada
Vinski1*, Dollar2, Andi Kurniawan Nugroho3, Natasha Cinta
Vinski4
Celltech Stem Cell Centre
Laboratory and Banking, South Jakarta, DKI Jakarta, Indonesia1,2,3,4
Email: drdeby@eradunia.com1*, andikn@usm.ac.id2, natashacintavinski@gmail.com3, drdollar18@gmail.com4
|
KEYWORDS |
ABSTRACT |
|
Quantum Stem Cell
Therapy, Autoimmune Diseases, Treatment. |
This qualitative descriptive study explores the effectiveness of
quantum stem cell therapy in addressing autoimmune diseases, with a specific
focus on immune modulation and tissue regeneration. Conducted at the Vinski Regenerative Center, the study involved two female
patients, aged 53 and 59, who underwent repeated stem cell injections over a
specified period. Patient data, encompassing demographic information and
disease characteristics, were collected through comparative literature
reviews and laboratory analyses. Preliminary findings reveal promising
therapeutic outcomes, manifesting as improvements in symptoms such as
weakness, joint pain, skin rashes, and fever. Stem cell therapy exhibited
potential for immune suppression and tissue repair, thereby offering a novel
avenue for managing autoimmune diseases. Further research is imperative to
refine treatment protocols and elucidate underlying mechanisms, ultimately
enhancing patient care and outcomes in autoimmune disease management. |
|
DOI: 10.58860/ijsh.v3i4.186 |
|
Corresponding
Author: Deby Susanti Pada Vinski *
Email: drdeby@eradunia.com
INTRODUCTION
Autoimmune diseases represent a series of diseases where the
immune system's response to self-antigens leads to tissue damage and
dysfunction. This group of diseases includes diseases that can affect certain
body systems, and certain organs, or can be systematic. In most autoimmune
diseases, there is a clear difference in prevalence between women and men,
where the diseases occur more often in women (Ngo et al., 2014). A hallmark of
autoimmune diseases is the failure of the immune system to distinguish between
non-self and self, which causes it to target healthy tissue, resulting in
tissue injury. Autoimmune diseases cause damage to human organs because they
damage healthy cells in the body (Janeway et al., 2013).
More than 80 diseases are classified as autoimmune diseases. Some
of them are well known, such as multiple sclerosis, type 1 diabetes, rheumatoid
arthritis, and lupus, while other autoimmune diseases occur rarely and are
difficult to diagnose. Patients suffering from rare autoimmune diseases can receive
a proper diagnosis only after several years of testing. There is no cure for
most autoimmune diseases, while some require lifelong treatment to relieve
symptoms (NIH, 2024). Although there are several types of autoimmune diseases,
many have similar symptoms that include fatigue, skin problems, recurring
fever, swelling and pain in the joints, digestion problems, swollen glands, and
abdominal pain (Orbai, 2019). Many patients think that these common symptoms
are normal, and do not consult a doctor. However, when they enter the critical
phase of the disease, patients take the initiative to consult a doctor, which
leads to the initiation of treatment for autoimmune diseases. When a person
does not feel well, they should take immediate action and consult a doctor to
make a proper diagnosis and start treatment, especially when quantum stem cell
treatment is needed (Autoimmune Association, 2024).
Autoimmune diseases affect millions of people worldwide, causing
significant mortality and morbidity. A study (Conrad et al., 2023) conducted in
the United Kingdom, in which 22 million people participated, showed that
autoimmune diseases affect approximately one in 10 people, while the burden
increases over time at different rates depending on individual diseases. Regional,
seasonal, and socioeconomic differences that occur between several autoimmune
diseases suggest that environmental factors play a role in disease pathogenesis
(Conrad et al., 2023). Most conventional treatments for autoimmune diseases
consist of immunosuppressive agents used to control aberrant immune system
responses. However, immunosuppressive treatments cause unwanted effects and can
lead to long-term remission of the disease. Considering this, there is
increasing interest in discovering new therapies that will target the basic
mechanisms of autoimmune diseases, while minimizing unwanted effects (Rosenblum
et al., 2012).
In recent years, therapies based on stem cells for the treatment
of many diseases, including autoimmune diseases, have attracted a lot of
attention. Quantum stem cells represent a potential candidate for the treatment
of autoimmune diseases because they have distinct regenerative potential and
immunomodulatory properties (Hoang et al., 2022; Mohammedsaleh,
2022). Stem cells mediate immune suppression through several mechanisms,
including suppression of inflammation and immune modulation. Stem cells promote
the induction of T regulatory cells and inhibit the proliferation of T cells,
dendritic cells, and B cells, which causes an increase in immunological
tolerance. Immunosuppressive properties of stem cells occur as a result of
secreted biomolecules, which include prostaglandin E2 (PGE2), indoleamine
2,3-dioxygenase (IDO), nitric oxide (NO), transforming growth factor-β
(TGF-β), and interleukin 10 (IL-10). Because of these characteristics,
stem cells represent an ideal therapeutic tool for providing permanent,
long-term protection against autoimmunity. Although the modulatory properties
of stem cells have encouraged their use, the reported success rate has yielded
inconsistent clinical results, which may be attributed to a variety of factors
including an insufficient number of studies, incomplete data on stem cell
administration routes or doses, and variability in the duration of therapeutic
regimens. uses. To resolve these confusions, further research is needed, which
will contain all the data on the dose, administration of stem cells, etc.
(Srivastava, 2022).
The exact cause of autoimmune diseases is still unknown, while the
risk factors that increase the chances of developing autoimmune diseases are
known. Autoimmune disease risk factors include certain medications (you should
talk to your doctor about the side effects of antibiotics, statins, and blood
pressure medications), genetic predispositions (having relatives with an
autoimmune disease increases the risk of developing the disease because some
occur in families), if already suffer from one immune disease there is a higher
risk of developing another autoimmune disease, obesity, smoking, and infections
(Cleveland Clinic, 2021). However, although there is a predisposition to
autoimmune diseases in families, family members can be affected by various
disorders. For example, one family member may have rheumatoid arthritis and
another family member may have diabetes. Genetic susceptibility is not enough
to lead to the development of an autoimmune disease, other factors must also
contribute. Environmental factors in combination with genetic factors can be
the cause of the occurrence of autoimmune diseases in families. Another factor
is gender, where approximately 3/4 of autoimmune diseases are women (Better
Health Channel, 2012).
It has also been noticed that major hormonal changes in women,
such as menopause, childbirth, or pregnancy, affect the improvement or
worsening of autoimmune diseases (Better Health Channel, 2012). Bacterial and
viral infections can confuse the immune system and, combined with genetic
predisposition, lead to the development of autoimmune disease (Mount Sinai, 2024).
Infections associated with autoimmune diseases include viral infections such as
Epstein–Barr virus infection (Harley et al., 2018), SARS-CoV-2, Herpes simplex
virus, human T-lymphotropic virus type 1, Human Herpesvirus 6, Varicella
-Zoster Virus, Human Endogenous Retroviruses, Rubella, Coxsackie B4, Rotavirus,
and Cytomegalovirus, etc. (Sundaresan et al., 2023). The microbiome plays a
major role in maintaining the health of mammals. Changes in intestinal flora
can contribute to the development of autoimmune diseases. For example, in
systemic lupus erythematosus, a disturbance in the Firmicutes/Bacteroidetes
relationship has been described (De Luca & Shoenfeld,
2018).
METHOD
Research Design
This
research uses a qualitative descriptive method with a case study where the use
of quantum stem cell therapy for the treatment of autoimmune diseases offers
the potential to modify the natural recovery of knee osteoarthritis using stem
cell-based technology.
The qualitative
method was chosen because this research aims to explain and analyze the
effectiveness of quantum stem cell therapy in treating autoimmune diseases.
Research Settings
This
research was carried out at the Vinski Regenerative
Center, the main stem cell therapy clinic from the Celltech
Stem Cell Center laboratory located at Vinski Tower, Jl. Ciputat
Raya No. 22 A Pondok Pinang, South Jakarta, Indonesia
12310 and accredited by World Council of Stem Cell (WOCS), Geneva, Switzerland.
Participants
This
research involved 2 female patients aged 53 and 59 years who experienced
autoimmune diseases with various complaints such as often feeling weak, achy
muscles or joint pain, skin rashes, intermittent fever, swelling in the joints
or face, hair loss, difficulty concentrating, tingling in the hands or feet. Each
patient was studied using comparative literature studies and based on each
patient's laboratory results. Then, each patient undergoes quantum stem cell
therapy which is injected repeatedly over a certain period of time, which can
be 3 to 4 repetitions in 12 months. Patient data is collected periodically and
recorded in a notation book containing personal data and health history.
Techniques of Data Collection
Descriptive
data collection techniques have several types of techniques, including
interviews and observation. All participants provided baseline data, including
demographic information and disease characteristics.
Dose
Patients
are treated with live stem cells maintained at CELLTECH's Stem Cell and Banking
Laboratory, and therapy is performed at the Vinski Regenerative Center clinic.
Stem cells are stored in cryo tanks at -196 Celsius
(190 degrees below freezing), which is done in a “closed system” or “open
system”. Closed systems run independently of human operations and are fully
automated, whereas open systems use human operators to adjust the process as
needed. Closed systems are also referred to as quantum processes. This system
is considered more efficient and sterile than an open system because it
operates automatically in an isolated system and is separated from human
intervention. The main concentration of stem cells comes from the umbilical
cord and umbilical cord blood. Stem cells are stored in vials containing 20
million cells or more. The administration of stem cells for therapeutic purposes
depends on the type and severity of the disease, as this determines the number
of stem cells required.
The
stem cell dose is a combination of measuring the patient's, body weight (in
kilograms) multiplying it by a factor of one million, and additional other
conditions like DM, and hormonal deficiency. For example, the dose for a person
weighing 70 kg is 70 million stem cells (70 x 1,000,000). The allogeneic nature
of stem cells allows replacement and restoration of damaged cells at the target
location of recovery (Catarino et al., 2020). The dosage is also influenced by
the number of cells damaged and needing to be restored. The quality of recovery
depends on the dose. For example, a stem cell pack containing 20 million stem
cells may have minimal effects, while a higher dose will be more effective for
severe conditions.
Six
months after each round of stem cell therapy, patient progress is monitored to
determine treatment efficacy. The treatment used for this case study is
consistent with the success of stem cell treatments for diseases such as
Prader-Willi syndrome, autism, and several other diseases. The theory
underlying this case study is that stem cells have regenerative properties that
can rejuvenate and replace damaged cell tissue, and because of their allogenic
nature, stem cells can be applied to any part of the body (Tatullo
et al., 2020).
RESULTS
Symptoms of
Autoimmune Diseases
Symptoms and signs of autoimmune diseases depend on which
part of the body is affected. Many autoimmune diseases have symptoms that
include swelling, pain, heat, and redness. The above symptoms and signs are
also symptoms and signs of inflammation, which can cause other diseases.
Symptoms of autoimmune diseases can come and go. When they appear, symptoms can
be severe, while later there will potentially be remission and disappearance or
improvement of symptoms (MedlinePlus, 2018). The following are examples of
common autoimmune diseases and their symptoms.
Lupus
Systemic lupus erythematosus is a chronic autoimmune disorder
that can affect almost any organ. In lupus, the immune system becomes
hyperactive and antibodies attack healthy organs and tissues, including the
blood, lungs, heart, brain, kidneys, joints, and skin. Lupus is characterized
by periods of disease (flares) and periods of remission (wellness). In addition
to systemic lupus erythematosus, there are two other types of lupus:
drug-induced lupus and discoid lupus erythematosus. Drug-induced lupus usually
goes away when treatment is stopped, and the symptoms that do occur are usually
mild. Discoid lupus erythematosus mainly affects the skin, and the symptoms are
a rash on the scalp, face, or other places on the skin, and it can last for
days, or years, and repeat itself. Most patients with lupus have symptoms in only
a few organs. Common symptoms that occur with lupus include fever, arthralgia,
arthritis, skin rash, swollen ankles, anemia, pleurisy, photosensitivity,
butterfly rash over the nose and cheeks, Raynaud's phenomenon, abnormal blood
clotting problems, unexpected hair loss, ulcers in the mouth and seizures. When
they occur together, the above symptoms are of great importance. Each patient
suffering from lupus has symptoms specific to it, and no patient has identical
symptoms (New York State Department of Health, 2020).
Grave’s
Disease
Graves' disease often causes symptoms of hyperthyroidism and
can affect the skin and eyes. As with other autoimmune diseases, symptoms may
come and go over time. Symptoms of hyperthyroidism vary from patient to patient
and include irregular heartbeat, weight loss alone with increased appetite,
muscle weakness, trembling hands, heat intolerance, sweating, goiter, and
frequent bowel movements. Graves' ophthalmopathy is an eye disease that occurs
in one in three people with Graves' disease. Graves' ophthalmopathy occurs when
the immune system attacks the tissues around the eyes, and symptoms include
irritated and burning eyes, puffy eyes, sensitivity to light, swollen eyes,
pain and pressure in the eyes, double vision, and blurred vision. Symptoms of
Graves' ophthalmopathy may occur simultaneously with or before symptoms of
hyperthyroidism. Most people with Graves' ophthalmopathy have mild symptoms
that may occur even when thyroid function is normal and generally do not occur
after treatment. Although rare, patients with Graves' disease can have thick,
rough-textured, and reddish skin. This condition is called pretibial myxedema
or Graves' dermopathy and it mainly affects the lower legs, but it can also
develop on the tops of the feet and other areas of the skin. In most patients,
symptoms are painless and mild (National Institute of Diabetes and Digestive
and Kidney Diseases, 2019).
Psoriasis
The most common sign of psoriasis is raised, thick, and dry
patches on the skin that are often covered with a silvery-white coating (scale)
that itches. The signs and symptoms that will appear depend on the type of
psoriasis, the amount of psoriasis, and where it appears. Plaque psoriasis
causes the formation of plaques (raised, thick spots on the skin, varying in
size, where smaller plaques join together to form larger ones). Plaques usually
form on the elbows, scalp, lower back, and knees. However, they can form
anywhere on the skin and are usually itchy. Guttate psoriasis leads to the
formation of small bumps on the skin that mostly cover the legs, arms, and
trunk, and in rare cases the ears, scalp, and face. The bumps are scaly, small,
pinkish to salmon-colored, and disappear without treatment in a few weeks or
months, but can last a lifetime. Inverse psoriasis develops where skin touches
skin in places such as the crease of the buttocks, genitals, and armpits. At
sites of inverse psoriasis, red, smooth, raw-looking patches, painful or sore
skin, and a small ribbed white coating can be seen, which is not always present
(AAD, 2024).
Pustular psoriasis causes pus-filled bumps to
form on the hands and feet. The bumps do not contain bacteria even though the
skin looks infected. At the sites of pustular psoriasis, swollen, red skin
appears with bumps with pus, painful and sore skin, and brown spots when the
bumps dry up. (AAD, 2024).
Generalized pustular psoriasis (von
Zumbusch psoriasis) is a life-threatening condition
that rarely occurs. Von Zumbusch psoriasis causes
dry, sensitive, and red skin over most of the body. Within a day, bumps are
formed that are filled with pus and open. The skin is peeled and dried as the
manure dries within 24 to 48 hours. After the peeling of the skin, a glazed
smooth surface appears. Within a few days or weeks, the cycle can be repeated.
People with von Zumbusch psoriasis may have a fever,
muscle weakness, headache, and other symptoms (Romiti
et al., 2022). Erythrodermic psoriasis is life-threatening and causes the skin
on most of the body to look burnt, develop severe itching, rapid pulse, muscle
weakness, fever, and chills, and the person looks seriously ill. In addition,
hypothermia may develop. Erythrodermic psoriasis mainly occurs in people who
already suffer from another type of psoriasis and require immediate medical
attention (AAD, 2024).
Often, people who suffer from plaque psoriasis also develop
psoriasis on the nails, where there are small indentations on the nails, brown,
yellow, or white changes on several or one nail, rough, crumbling nails, nail
lifting, and the accumulation of skin cells under the nail. causes it to rise (Schons et al., 2014). Psoriatic arthritis affects the
joints and occurs in people with severe psoriasis. Early signs of psoriatic
arthritis are subtle and include heel pain, tender and swollen joints (in
fingers and toes), morning stiffness that resolves during the day, and swelling
behind the heel on the back of the heel (AAD, 2024).
Multiple
Sclerosis
Early symptoms and signs of multiple sclerosis include vision
changes (double vision, optic neuritis, and loss of vision), muscle weakness
that mainly affects one side of the body or face, or part of the body below the
waist, abnormal sensations or numbness mainly below the waist, or one side of
the body or faces. Common symptoms of multiple sclerosis include dizziness,
clumsiness, fatigue, loss of coordination and balance, difficulty with bladder
control, difficulty with cognitive functions such as reasoning, learning,
concentration, memory, and thinking, mood swings, tremors, and muscle stiffness.
Symptoms of multiple sclerosis vary from patient to patient and their severity
varies from day to day. Rarely, all symptoms occur at once, and several
symptoms may occur simultaneously (Cleveland Clinic, 2021a).
Myasthenia
Gravis
Myasthenia gravis leads to muscle weakness and often affects
the face and face, and over time it spreads to other parts of the body. When
the patient is tired, myasthenia gravis worsens and improves after rest. Other
triggers for symptoms include infections, stress, and certain medications.
Myasthenia gravis can lead to double vision, droopy eyelids, and difficulty
making facial expressions. Ocular myasthenia occurs when only the eye muscles
are affected. However, in most people, muscle weakness spreads to other parts of
the body within weeks, months, or years. It is unusual for other parts of the
body to be affected if they have not been affected within two years of the
onset of eye symptoms. When the disease affects the muscles in the chest,
throat, and mouth, it can lead to slurred speech, difficulty chewing,
accidental inhalation of food, choking, nasal, low, or hoarse voice, and
difficulty breathing. The spread of myasthenia gravis to the legs, arms, and
neck causes symptoms and signs that include muscle pain after use, difficulty
holding the head, difficulty performing physical tasks, and waddling walking.
The weakness that occurs is stronger in the hands compared to the feet and legs
(NHS, 2019).
Hashimoto’s
Disease
In the beginning, symptoms do not develop in all patients
with Hashimoto's disease. As the disease progresses, there is an increase in
the thyroid gland (goiter). A goiter is the first sign of Hashimoto's disease
and can create a feeling of fullness in the lower neck and should not be
painful. When Hashimoto's disease leads to hypothyroidism, symptoms include
excessive sleeping, lethargy, fatigue, constipation, mild weight gain, cold,
dry skin, bradycardia, muscle pain, joint stiffness, brittle dry hair, loss of
skin, and slow growth. hair loss, depressed and low mood, swollen face and
eyes, difficulty concentrating, memory problems, irregular or heavy periods,
male and female infertility, and decreased libido (Cleveland Clinic, 2017).
Crohn's
Disease and Ulcerative Colitis
Symptoms of Crohn's disease and ulcerative colitis can be
mild or severe and different for each person, depending on the location of
inflammation in the intestines. During a flare, the most common symptoms
include frequent diarrhea, abdominal pain, fatigue, tiredness, loss of
appetite, fever, high fever, weight loss, and anemia.
Rheumatoid
Arthritis
In the early stages of rheumatoid arthritis, pain and
tenderness in the joints occur, while in the later stages of the disease,
swelling or redness occurs in the joints. Symptoms of rheumatoid arthritis
include morning stiffness that usually lasts 30 or more minutes, joint
involvement on both sides of the body, and small joints such as the ankles,
feet, or wrists are affected first, usually more than one joint is affected. In
addition, some patients suffering from rheumatoid arthritis may experience low
temperature and severe fatigue. As with other autoimmune diseases, symptoms can
come and go (Mohammed et al., 2023).
Guilliam-Barre Syndrome
Guilliam-Barre syndrome
usually first affects the hands or feet, before spreading to other parts of the
body, and begins several days to weeks after an infection such as the flu or
stomach bug. Early symptoms develop over hours or days and include chills,
numbness, pain, muscle weakness, and problems with coordination and balance.
The above-mentioned first symptoms usually affect both sides of the body at the
same time. Later symptoms of Guillim-Barre syndrome
develop over several days or weeks, may be mild or severe, and include double
or blurred vision, inability to move the face, arms, or legs, difficulty
walking, difficulty breathing, severe or persistent pain, difficulty urination,
chewing or swallowing problems, difficulty speaking, and constipation. The most
severe symptoms usually appear within four weeks and remain stable for several
weeks or months before gradually improving (NHS, 2017).
Vasculitis
Depending on the severity of the disease, the type, and the
affected organs and blood vessels, the symptoms of vasculitis differ. Common
symptoms of vasculitis include fever, fatigue, weight loss, and loss of
appetite. Vasculitis can cause problems with the nose and ears (ringing in the
ears, runny nose, open sores in the nose, inner ear infections, deafness,
etc.), eyes (itching, redness, changes in vision and burning), gastrointestinal
problems (pain, diarrhea, open sores in the stomach and mouth area), genital
ulcers, scalp sensitivity, headache, heart palpitations, joint pain, nerve
problems (burning, numbness, weakness and pain in various parts of the body),
lung problems, skin rash, red or purple spots on the skin, bruising, itching,
hives, calluses of the palms and feet, swelling of the palms and feet,
gangrene, swelling of the throat and mouth, dry and swollen lips or tongue.
Narrowed blood vessels due to vasculitis block normal blood flow and can lead
to life-threatening complications including arrhythmia, anemia, coronary heart
disease, heart attack, deep vein thrombosis, low or high blood pressure,
myocarditis, kidney disease, transient ischemic attack, and stroke. (NIH,
2023).
Treatment of
Autoimmune Diseases
Most of the diseases that are classified as autoimmune
diseases cannot be cured. However, the symptoms that occur in these diseases
can be alleviated and their recurrence can be prevented. Treatment depends on
the type of autoimmune disease, the symptoms that occur, and their severity (Chandrashekara, 2012). Treatments for autoimmune diseases
include drugs (Chandrashekara, 2012) and hormone
replacement therapy (Lateef & Petri, 2012). Medicines used for autoimmune
diseases include non-steroidal anti-inflammatory drugs (NSAIDs) including
naproxen and ibuprofen (to treat fever and pain), immunosuppressive drugs that
inhibit disease progression and maintain organ function such as corticosteroids,
and anti-TNF drugs that prevent inflammation caused by autoimmune disease (Li
et al., 2017). Hormone replacement therapy is introduced to patients suffering
from an autoimmune disease that inhibits the production of certain hormones in
the body. For example, people with thyroiditis receive thyroid hormone therapy
(Wiersinga, 2001; Oftedal
& Wolff, 2020), while people with type 1 diabetes receive insulin as
therapy (Bitoska et al., 2016).
Complications
of Autoimmune Diseases
Autoimmune diseases can lead to serious complications
including heart damage (Pan et al., 2022), nerve damage, anxiety disorders,
depression (Ravan et al., 2021), and deep vein
thrombosis (Zöller et al., 2012).
Prevention of
Autoimmune Diseases
Because most autoimmune diseases are related to genetic
factors, their development cannot always be prevented. However, it is possible
to reduce the risk of developing autoimmune diseases with regular exercise, not
smoking, regular hand washing to avoid bacterial and viral infections, using
protective equipment to avoid exposure to harmful chemicals, and maintaining a
healthy body weight. In addition, the introduction of aggressive treatment in
persons who have a high risk of developing autoimmune diseases can prevent the
appearance of symptoms (Shepshelovich & Shoenfeld, 2006).
Quantum Stem
Cell Therapy for Autoimmune Diseases
Therapy with quantum stem cells for autoimmune diseases
allows to provide positive efficiency to patients. Stem cells have plasticity
and homing and have shown high efficacy in halting damage due to the immune
response and returning body function to normal levels while repairing damage at
the cellular level with reduced inflammation and increased blood flow (Mohammedsaleh, 2022). In vitro studies have reported that
mesenchymal stem cells (MSCs) have immunosuppressive effects and
immunomodulatory properties on the proliferation of MHC-mismatched lymphocytes,
dendritic cells, NK cells, B cells, active and memory T cells (Choi, 2009). At
the Celltech Stem Cell Center, MSCs are produced from
the umbilical cord and processed through a quantum system (Celltech
Stemcell Centre, 2024). The quantum method is carried
out in a closed system, which reduces the occurrence of human error, and the
cells multiply in a shorter time, from 100 to 300 times more than the number of
multiplied conventional cells. The cells obtained by the quantum method are of
the best quality and are stored in the Stem Cell Bank or Tissue Cell Bank, and
can later be used for the future medical needs of the patient or his family
(Song et al., 2020; Hanley et al., 2014).
Stem
cells have the ability to transform into the cells of organs that are damaged
when they come into contact with those particular organs, and that is why they
are used for the treatment of autoimmune diseases. They can be used to treat
damaged muscles and nerves in the same way. Stem cells can slow the progression
of the disease or stop it altogether. In cases of severe disease, more stem
cell treatments are generally required. The success rate of stem cell therapy
is proportional to the patient's age, condition, and disease duration (Ebrahimi
et al., 2021).
Case study
Basic
characteristics of participants
1.
Patient A, Female, 59 yo
Symptoms before therapy: 17 years taking medicine with a history of
Pemphigus Vulgaris, hospitalized for 5 times, frequently feeling
weak, sore muscles or joint pain, diabetes, high blood pressure, skin rashes,
intermittent fever, swelling in the joints and face, hair loss, difficulty
concentrating, and tingling in the hands or feet.
Treatment
Time Points Average: 12 months (3x therapy)
Progress after therapy:
·
Patient A has been free from drugs for 2 years.
·
Blood sugar levels become normal, and the blisters on Bengasur's
skin disappear.
·
Muscle strength returns
·
Able to walk long distances
·
Skin becomes healthier
2. Patient B, Female, 53
yo
Symptoms before therapy: Osteoarthritis grade 3 with pain level 8
(severe pain), inflammation of left toe, frequently feeling weak, redness and
swelling in the joints, especially the joints of the fingers, the knee joint
feels painful when used for activities, such as walking for a long time, going
up and down stairs or squatting.
Treatment
Time Points Average: 12 months ( 3x therapy)
Progress after therapy:
·
Normal cortical outline, no bone defect is detected.
·
Irregularity of the right subchondral bone layer at the adjacent
4th 5th tarsometatarsal joint, associated with mild capsular distension and
joint effusion.
·
Another tarsometatarsal joint in the 1st, 2nd, and 3rd fingers
appeared normal.
·
Adjacent flexor and extensor tendons appeared normal.
·
CFUS: No evidence of increased vascularization around the affected
joints as well as tendon-tendon sheaths.
·
Plantar plates revealed intact.
·
Soft tissue appeared normal.
·
Currently, there is no sign of active inflammation in the joint as
well as tendon-tendon sheath.
·
Arthritis and capsular distention are slightly reduced.
·
The body feels lighter and fresher, strong enough to walk long
distances.
The
properties and characteristics of quantum stem cells, apart from proliferation
and differentiation, stem cells also secrete or release cytokines or dissolved
substances that contain many anti-inflammatory substances, as well as
substances that contain ingredients to stimulate dormant cells, and to grow
blood vessels, and activation of regeneration as well as for homing home to
tissues or organs that require it. So in this case study, quantum stem cells
appear to be able to improve the symptoms felt by the patient for the better
because the stem cells regenerate damaged cells related to autoimmune disease.
The effects of quantum stem cell therapy are different for each patient and
depend on the condition of each patient, but almost all patients experience
changes for the better.
By
carefully collecting and analyzing the data, we discovered several useful
findings. Age, gender, and symptoms of various types of autoimmune diseases
were the basic characteristics of our analysis. Throughout the investigation, interesting
changes in immune cell populations emerged. Natural cell regeneration proves
the potential of quantum stem cell therapy to influence the body's immune
balance. Although these results are encouraging, their significance requires
thorough contextualization within the broader context of autoimmune disease
management.
CONCLUSION
This
chapter concludes our investigation and analysis of the effectiveness of autoimmune
treatment with quantum stem cells. In an effort to advance our understanding of
this new therapeutic approach, we conducted a comprehensive investigation into
the potential benefits of quantum stem cells. Autoimmune diseases represent a
heterogeneous group of disorders with individual genetic, environmental, and
etiological factors. Autoimmune is defined as an immune response to a tissue's antigens
caused by tolerance loss. The prospect of exploiting the innate properties of
quantum stem cells for immune modulation represents a new front in the fight
against autoimmune diseases, as researchers continue to investigate their
therapeutic potential. Our analysis of the potential of quantum stem cells has
revealed tantalizing clues about new therapeutic pathways for autoimmune
diseases. This study serves as a springboard that demonstrates the power of
interdisciplinary collaboration, scientific inquiry, and collective commitment
to advancing medical knowledge. In the future, treating patients with this
technology will become relatively routine because this technology has
progressed relatively rapidly, and more research is being carried out,
especially on stem cells from the umbilical cord.
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