DM, or Diabetes mellitus, is a chronic illness that is rather common in Indonesia. Understanding the risk factors diabetes mellitus might help the scheme of diabetes mellitus patiens work better . To identify the variables that increase the risk of diabetes mellitus in the Kedaton Health Center Region. In June 2024, a cross-sectional study was carried out at the Kedaton Health Center in the Cirebon Regency. Patients who visited the Kedaton Health Center for treatment served as the research subjects; 158 responders made up the sample size in total. Consecutive sampling was the sample method employed. A blood glucose test and a questionnaire were used to gather data. Logistic regression and the chi-square test were employed for data analysis. Age (P = 0.001, OR = 6.98: CI95% = 2.46-19.79), family history of diabetes (P = 0.001, OR = 0.058: CI95% = 0.019-0.184), diet (P = 0.007, OR = 0.337: CI95% = 0.152-0.748), socioeconomic status (P = 0.019, OR = 3.557: CI95% = 1.237-10.225), and education level (P = 0.822, OR = 0.757: CI95% = 0.067-8.575) were found to be significantly associated with diabetes mellitus of various kinds. In this investigation, the incidence of DM was not correlated with gender, weight, or physical activity. a number of factors, including age, diet, family history of diabetes, socioeconomic status, and education level, significantly impact the incidence of diabetes mellitus. Age is the most significant risk factor.