Complete Androgen insensitivity Syndrome (CAIS) is a disorder of androgen hormone resistance characterized by female phenotypes in individuals with XY karyotype. The typical clinical feature for CAIS is primary amenorrhea in adolescents, or inguinal swelling in infants. Women with this disorder have breast development and puberty growth at an appropriate age, but not menstruation. In this paper reported cases of women aged 38 years came with complaints of an enlarged lump in the left inguinal since 10 years. During his life the patient has never experienced menstruation. The lump in the patient is then removed, histological examination is performed, and a semimoma feature is obtained. The karyotype examination is performed and shows the XY sex chromosome.